We would thus argue that activation of FFA3 should suppress catecholamine release and thus sympathetic function. to produce voltage-dependent inhibition of N-type Ca2+channels (Cav2.2) in sympathetic neurons. In addition to acetate and propionate, we show that -hydroxybutyrate (BHB), a metabolite produced during ketogenic conditions, is also an FFA3 agonist. This contrasts with previous interpretations of […]