There was a modest numeric increase in T1/2as well, but T1/2calculation was confounded by longer infusion times at the higher dose levels (up to 7h). MDX-447 + G-CSF (group 2). Hypotension was the predominant dose-limiting toxicity (DLT) in both treatment groups, with seven patients experiencing grade 3 events. MDX-447 half-life (T1/2) ranged from 1.9 to […]