PTPN22 is one of the highest confidence direct targets of Foxp3. ACPA- RA patients, ACPA+ cases experienced greater imbalances between peripheral CD4+ Mouse monoclonal to p53 T cell subsets, mainly manifested as an increase in T-helper 1 (Th1) cells ( 0.001) and decrease in regulatory T (Treg) cells (= 0.029). This makes these patients more […]