(F) Histograms showing the average signal intensities of centromeric pT120-H2A observed in the experiments described in (E); n?=?73C107 cells per condition. kinase Bub1 functions in the spindle assembly checkpoint (SAC) and in chromosome congression, but the role of its catalytic activity remains controversial. Here, we use two novel Bub1 inhibitors, BAY-320 and BAY-524, to demonstrate […]