Day: November 10, 2022

Interestingly, activated PKD1 quickly dissociates from your plasma membrane, returns to the cytoplasm, and accumulates in the nucleus. PAK inhibitors did not interfere with G protein-coupled receptor activation-induced quick translocation of PKD1 to the plasma membrane but strikingly prevented the dissociation of PKD1 from your plasma membrane and blunted the phosphorylation of nuclear targets, including […]