?(Fig.55 < 0.05). a peroxynitrite scavenger. When ICa,L was prestimulated by 10 M milrinone, an inhibitor of cGMP-inhibited phosphodiesterase (type III) activity, SP/NO failed to further increase ICa,L. In cells incubated in pertussis toxin (3.4 g/ml for 6 h; 36C), ACh failed to affect ICa,L, but 100 M SP/NO or 10 M milrinone still increased […]