Furthermore, we showed that EGFR, FGFR2, IGF1R, and VEFGR2 were upregulated in Tzm-resistant cell lines. 3 were downregulated by trastuzumab treatment significantly. All upregulated antigens had been linked to endothelial and stem cell phenotypes, recommending that trastuzumab treatment could be correlated to switching to a vascular phenotype, specifically, vasculogenic mimicry DSP-0565 (VM). Many VM markers […]