In contrast, recombinant (r) IFN- cotreatment limited YTS-induced purging of islet T cells to less than 2-fold (Figure 4, C and D). T cells. These findings demonstrate that Ab binding of CD4 and CD8 interrupts a feed-forward circuit by suppressing T cellCproduced cytokines needed for manifestation of chemotactic cues, leading to quick T cell egress […]