In individuals with SLE, this ligand is upregulated by activation from the Syk pathway (48, 49). existence of circulating autoantibodies, lymphopenia, aberrant T cells, and proinflammatory cytokines along with faulty regulatory mechanisms, resulting in immune-mediated harm to tissue. Lupus sufferers tend to be treated with immune-suppressants and they are immune-compromised and even more susceptible to […]