3F). Activation of hepatic MAIT cells by IL-12 and IL-18 upon bacterial infection We recently demonstrated that overnight bacterial activation of Madecassoside healthy PBMCs activated MAIT cells to produce IFN- directly via MR1 as well while indirectly via IL-12- and IL-18-dependent mechanisms [13]. ssRNA40. Mechanistically, ssRNA40 induced hepatic monocytes to produce IL-12 and IL-18 cytokines, […]